The Spliceosome

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The Spliceosome

Postby stcordova » Sat Mar 24, 2018 4:02 am

The spliceosome is one of the most complex molecular machines that are found in multi cellular creatures like humans.

Bacteria are creatures that are as a subset of prokaryotes and animals are classified as subset of eukarytoes. All animals, as far as I know, have spliceosomes.

The genes of bacteria and animals obey different grammatical constructs. The grammar between the two groups is similar, but not exact, but more importantly the machines that process the animal gene grammar is radically different than machines (or lack thereof) that process bacterial gene grammar.

To understand the difference consider this conceptual diagram of a gene, it is composed of parts called exons and introns. Here is a simple conceptual diagram of a gene:


Now, bacteria and animals have introns, but animals have a special kind of intron known as a spliceosomal intron, and animals have a LOT more introns than bacteria since many bacterial genes have no introns and NO bacterial genes have that special kind of intron known as a spliceosomal intron.

A special machine has to SPLICE out the intron and merge the exons together to create something known as an mRNA transcript which then can become a protein.
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